What Is Niacinamide


Share post:

Desk of Contents[Hide][Show]

As busy mamas, we don’t have plenty of time to dedicate to our skincare routines. That’s why it’s nice to have some “go-to” pure magnificence merchandise that maximize our time and provides us nice advantages—ones that not solely give us glowing pores and skin however are additionally fast and straightforward to make use of. 

Niacinamide is one skincare ingredient I like to recommend making part of your pure skincare routine.

What Is Niacinamide?

This nutrient, additionally known as nicotinamide, is likely one of the types of vitamin B3, niacin. It’s a water-soluble vitamin that’s present in meat within the type of niacinamide and plant meals as nicotinic acid. 

As a result of niacin is water-soluble, we want it every day. Water-soluble nutritional vitamins are absorbed rapidly and aren’t saved by our our bodies, so we have to replenish them every day.

What Is Niacinamide Good for? 

The physique wants it to transform the meals you eat into vitality. Niacin additionally helps with necessary processes within the physique, like creating hormones. It’s an necessary nutrient for metabolism, which implies it’s additionally necessary for the expansion and restore of the physique’s tissues.

That’s particularly evident in its capability to advertise well-nourished, lovely pores and skin. In any case, skincare begins on the within with good diet. 

Find out how to Get Niacinamide

Niacin and niacinamide are broadly present in meals and are sometimes added to fortified grain merchandise to make sure we get the advisable quantity—round 14-18 mg per day. It is usually accessible in complement kind. You may as well use it topically (as a lotion, gel, or serum) for quite a lot of skincare considerations. 

Niacinamide in Meals

Crimson meat, hen, and fish are some meals with the very best quantities of this vitamin, together with peanuts and occasional. Barley, wheat, beans, soybeans, potatoes, and rice have reasonable quantities, whereas vegatables and fruits have decrease quantities. 

When you’ve got a compromised intestine, you might have a tough time absorbing niacinamide from meals, and dietary supplements could also be extra useful to get the quantity you want.

Niacin (additionally known as nicotinic acid) could cause a “niacin flush” due to its results on blood vessel capillaries. It causes the capillaries to increase rapidly, rising the blood circulate to the pores and skin’s floor, which causes redness, heat, and itchiness in that space of the pores and skin. That’s why I want the niacinamide type of this B-vitamin.

Niacinamide in Supplementation

A niacinamide dietary complement might assist enhance pores and skin situations, shield the pancreas in Kind 1 diabetes, and help the kidneys. 

In addition to supporting kidney and pancreatic well being, the primary well being advantage of taking this complement pertains to pores and skin well being:

  • Anti-inflammatory – when taken as a complement and utilized to the pores and skin. A evaluate research discovered it to be useful in each zits and rosacea.
  • Lowering zits – and breakouts (which I nonetheless get once in a while). 
  • Anti-aging – helps sluggish the growing older course of and has an anti-aging impact
  • Protecting in opposition to pores and skin most cancers – A 2015 research printed within the New England Journal of Medication discovered that supplementing (500 mg twice every day) diminished precancerous pores and skin harm in individuals who had been identified with pores and skin most cancers prior to now 5 years. 

Niacinamide in Skincare

Many merchandise use niacinamide as a skincare ingredient. You’ll find it in cleansers, toners, gels, serums, lotions, eye lotions, and moisturizers. It helps with many alternative points of pores and skin well being, together with enhancing the pores and skin barrier, hydration, night out pores and skin tone, and defending in opposition to harm. 

Skincare merchandise like cleansers and make-up removers that wash off in all probability don’t supply sufficient contact time along with your pores and skin to make a lot of an affect. It’s higher to make use of merchandise that keep on the pores and skin, like serums, moisturizers, or lotions.

Dermatologists suggest a topical utility of niacinamide for some particular pores and skin points in addition to normal skincare. Listed here are some particular issues that it helps with:  


Hyperpigmentation is a situation the place you develop darker patches in your pores and skin and is attributable to the pores and skin creating extra melanin. In a scientific research printed within the British Journal of Dermatology, a bunch used niacinamide moisturizer for 4 weeks and located that hyperpigmentation considerably decreased.


A 2011 evaluate research notes that dermatologists have used nicotinamide for over 40 years for rosacea and different pores and skin situations. A randomized managed trial carried out in 2005 examined a moisturizer in sufferers with rosacea. The cream, utilized twice every day for 4 weeks, improved the pores and skin barrier and improved the situation in rosacea victims.

Dry Pores and skin

Dry pores and skin may be a difficulty as we age or based mostly on the local weather that we stay in. When you’ve got dry pores and skin, you may need to strive it. A research of sufferers with dry pores and skin who utilized nicotinamide cream twice every day to their face over 4 or eight weeks confirmed a major lower within the lack of moisture within the pores and skin and an enchancment of their dry pores and skin situation.


This skincare ingredient may also assist with zits and blemishes. In decreasing the severity of zits situations, one research of 4% nicotinamide gel discovered it was corresponding to a 1% clindamycin gel (the usual antibiotic therapy). 

Anti-Growing older (fantastic traces and wrinkles)

In a research of fifty ladies with indicators of growing older (together with fantastic traces and wrinkles), a 5% concentrated product was utilized to half of their face twice every day for 12 weeks. On the opposite half of their face, they used a placebo product. 

On the finish of the research, the edges of the faces that used the therapy confirmed important enchancment total, together with a discount in fantastic traces and wrinkles, extra even pores and skin tone, improved coloration (much less yellowing), and higher elasticity. 

Pores and skin Most cancers

Niacinamide’s anti-aging results can also assist stop pores and skin most cancers. In a 2019 research printed within the Worldwide Journal of Molecular Science, researchers identified that growing older is a significant danger issue for the event of pores and skin most cancers.

The physique wants niacinamide to supply NAD+, a coenzyme that protects the pores and skin from gene-damaging toxins. When genes are broken, it may possibly lead down a path towards most cancers. The depletion of NAD+ in our our bodies is usually related to the ailments of growing older, which embrace most cancers.

That’s the place replenishing niacinamide within the pores and skin, whether or not by way of dietary supplements or skincare merchandise, may help preserve pores and skin wholesome and youthful. 

What Is Niacinamide Serum?

A serum is a lightweight, quick-absorbing skincare product that delivers a concentrated dose of niacinamide. The focus within the gel-like liquid may be anyplace from 2% to 10%. A typical dosage is 4%.

When used topically, this nutrient may help promote the expansion of the pores and skin’s ceramide (lipid) barrier. This helps stop water loss and retain moisture.

Niacinamide is useful for all pores and skin sorts, whether or not your pores and skin is oily, dry, or a mixture. In the event you’re involved about delicate pores and skin, it is rather soothing, so long as there aren’t different substances within the product that may irritate your pores and skin. 

When in search of a skincare product, like a cleanser, serum, or gel, take note of what else is in it. You’ll need to ensure that it’s freed from parabens, phthalates, and artificial fragrances. 

If you wish to make your individual skincare product with niacinamide, right here’s a recipe for a DIY silky moisturizer I like!

Find out how to Use a Serum

It’s finest to make use of the serum after cleaning, firming, and exfoliating. Then you possibly can work with a clear palate. Apply it evenly over your face moderately than simply utilizing it on track/downside areas. 

Comply with up your niacinamide product with any moisturizers or sunscreen merchandise you need to apply.

It’s an ingredient you should use year-round. You gained’t have points making use of it earlier than going within the solar, and there’s no motive to take breaks except you’re experiencing unwanted side effects.

Dangers & Facet Results 

There are a couple of potential dangers or unwanted side effects to contemplate when utilizing this highly effective B vitamin: 

Inner Dietary supplements

Potential unwanted side effects of taking dietary supplements embrace:

  • Abdomen upset
  • Gasoline
  • Dizziness
  • Rash or itchy pores and skin

These aren’t frequent, however in the event you begin experiencing a few of these shortly after including a complement kind, strive eradicating it and see if the signs enhance. 

Taking extreme quantities over time may result in diabetes, Parkinson’s illness, and liver harm. You’ll need to ensure that your vitamin B ranges are inside a standard vary once you get your yearly bloodwork performed. 

Topical Niacinamide

Potential unwanted side effects from utilizing a topical model are normally noticeable straight away and embrace: 

  • Gentle redness 
  • Itching 
  • Slight burning sensation

In the event you use a focus of 5% or underneath, these are usually unusual and gentle once they happen. Increased concentrations usually tend to create points.

FAQs: Can You Combine Niacinamide and _________?

As you’re placing collectively your pure skincare routine, you may surprise about combining completely different merchandise or substances. I’ll cowl a couple of of these frequently-combined substances under and the most effective order to make use of them so that you get essentially the most out of them.

Niacinamide & Retinol Serum

Retinol is a typical antioxidant serum used on the face. Retinol is stronger than nicotinamide and is understood to trigger irritation, dry pores and skin, and redness. You need to use retinol and niacinamide concurrently, however ideally, you’d apply retinol first and observe it with niacinamide. It’s because the retinol tends to be a bit irritating to the pores and skin, and following up with niacinamide helps soothe the pores and skin and assist it to heal. 

Learn this submit to be taught extra about retinol/retinoids. Remember that retinoids might trigger solar sensitivity, although. 

Niacinamide & Vitamin C Serum

If utilizing a vitamin C serum, apply it at a special time than the niacinamide skincare product. It could possibly stop the vitamin C serum from working because it ought to, inactivating it. If uncovered to warmth, vitamin C might react with niacinamide, turning it into niacin (nicotinic acid) and worsening the pores and skin. 

Ideally, use the niacinamide serum within the morning and the vitamin C serum at night time.

Niacinamide & Hyaluronic Acid

Hyaluronic acid is one other skincare ingredient that may pair nicely with niacinamide. Each work so as to add moisture to the pores and skin, decrease irritation, stimulate collagen manufacturing, and usually promote therapeutic. 

These two substances are sometimes discovered collectively in skincare merchandise. They complement moderately than compete, and every enhances the opposite’s moisturizing properties. The hyaluronic acid is nice for enhancing moisture and tightening the pores and skin, and the niacinamide provides an exquisite pure radiance.

If utilized individually, use the hyaluronic acid first since it may possibly draw water into the pores and skin, conserving it moist all day. Then add the niacinamide, which helps shield the pores and skin’s floor and maintains a wholesome stage of pure oils.

Niacinamide & Salicylic Acid 

Salicylic acid can work nicely alongside niacinamide, as it really works as an astringent, cleansing out the pores and serving to to deal with zits. Niacinamide then provides again the moisture that the drying, typically irritating salicylic acid might take away.

In the event you use them collectively, apply the salicylic acid first after which use the niacinamide serum.

This text was medically reviewed by Madiha Saeed, MD, a board-certified household doctor. As at all times, this isn’t private medical recommendation and we suggest that you just discuss along with your physician.

Have you ever tried niacinamide skincare merchandise? How does it give you the results you want? Do you mix it with different serums or substances like those talked about? 

  1. Institute of Medication (US) Standing Committee on the Scientific Analysis of Dietary Reference Intakes and its Panel on Folate, Different B Nutritional vitamins, and Choline. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline. Washington. (DC): Nationwide Academies Press (US); 1998. 6, Niacin.
  2. Hill, L. J., & Williams, A. C. (2017). Meat Consumption and the Dose of Vitamin B3 – Nicotinamide: Explanation for the Causes of Illness Transitions, Well being Divides, and Well being Futures?. Worldwide journal of tryptophan analysis : IJTR, 10, 1178646917704662.
  3. Ods.od.nih.gov. 2011. Workplace of Dietary Dietary supplements – Niacin.
  4. Jacobson T. A. (2010). A “scorching” matter in dyslipidemia administration–“ beat a flush”: optimizing niacin tolerability to advertise long-term therapy adherence and coronary illness prevention. Mayo Clinic proceedings, 85(4), 365–379. https://www.mayoclinicproceedings.org/article/S0025-6196(11)60429-1/fulltext
  5. Hegyi, J., Schwartz, R. A., & Hegyi, V. (2004). Pellagra: dermatitis, dementia, and diarrhea. Worldwide journal of dermatology, 43(1), 1–5. 
  6. Niren N. M. (2006). Pharmacologic doses of nicotinamide within the therapy of inflammatory pores and skin situations: a evaluate. Cutis, 77(1 Suppl), 11–16.
  7. Surjana, D., & Damian, D. L. (2011). Nicotinamide in dermatology and photoprotection. Skinmed, 9(6), 360–365.
  8. Ying W. (2008). NAD+/NADH and NADP+/NADPH in mobile features and cell demise: regulation and organic penalties. Antioxidants & redox signaling, 10(2), 179–206. 
  9. Chen, A. C., Martin, A. J., Choy, B., Fernández-Peñas, P., Dalziell, R. A., McKenzie, C. A., Scolyer, R. A., Dhillon, H. M., Vardy, J. L., Kricker, A., St George, G., Chinniah, N., Halliday, G. M., & Damian, D. L. (2015). A Section 3 Randomized Trial of Nicotinamide for Pores and skin-Most cancers Chemoprevention. The New England journal of drugs, 373(17), 1618–1626. 
  10. Hakozaki, T., Minwalla, L., Zhuang, J., Chhoa, M., Matsubara, A., Miyamoto, Okay., Greatens, A., Hillebrand, G. G., Bissett, D. L., & Boissy, R. E. (2002). The impact of niacinamide on decreasing cutaneous pigmentation and suppression of melanosome switch. The British journal of dermatology, 147(1), 20–31.
  11. Draelos, Z. D., Ertel, Okay., & Berge, C. (2005). Niacinamide-containing facial moisturizer improves pores and skin barrier and advantages topics with rosacea. Cutis, 76(2), 135–141.
  12. Soma, Y., Kashima, M., Imaizumi, A., Takahama, H., Kawakami, T., & Mizoguchi, M. (2005). Moisturizing results of topical nicotinamide on atopic dry pores and skin. Worldwide journal of dermatology, 44(3), 197–202.
  13. Shalita, A. R., Smith, J. G., Parish, L. C., Sofman, M. S., & Chalker, D. Okay. (1995). Topical nicotinamide in contrast with clindamycin gel within the therapy of inflammatory zits vulgaris. Worldwide journal of dermatology, 34(6), 434–437.
  14. Bissett, D. L., Rectangular, J. E., & Berge, C. A. (2005). Niacinamide: A B vitamin that improves growing older facial pores and skin look. Dermatologic surgical procedure : official publication for American Society for Dermatologic Surgical procedure [et al.], 31(7 Pt 2), 860–865.
  15. Fania, L., Mazzanti, C., Campione, E., Candi, E., Abeni, D., & Dellambra, E. (2019). Function of Nicotinamide in Genomic Stability and Pores and skin Most cancers Chemoprevention. Worldwide journal of molecular sciences, 20(23), 5946.Rolfe H. M. (2014). A evaluate of nicotinamide: therapy of pores and skin ailments and potential unwanted side effects. Journal of beauty dermatology, 13(4), 324–328.

Supply hyperlink


Please enter your comment!
Please enter your name here


Related articles